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Year : 2012  |  Volume : 1  |  Issue : 3  |  Page : 178-180

Clear cell renal carcinoma with areas of chromophobe renal cell carcinoma

Department of Pathology, JSS Medical College, Constituent College of JSS University, Mysore, India

Correspondence Address:
Rekha Thodavadi Subbanna
818, 13th Main, 4th Stage, T. K. Extension, Mysore - 570 009
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-344X.105082

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The classification of renal cell carcinoma (RCC) is based upon various histological features which aids in determining the treatment and prognosis. We report a unique case of RCC displaying features of predominantly clear cell RCC with areas of chromophobe RCC in an unusual edematous background. The tumor cells from chromophobe RCC were positive for Hales colloidal iron stain. On Immunohistochemistry majority of them were positive for vimentin and CD10, the markers of clear cell RCC with scattered cells positive for cytokeratin 7, marker of chromophobe RCC. It was grade 4 malignant tumor according to Fuhrman nuclear grading.

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