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Year : 2015  |  Volume : 4  |  Issue : 2  |  Page : 108-110

Porphyria Cutanea Tarda: A rare metabolic condition in India

1 Department of Pharmacy Practice, Jagadguru Sri Shivarathreeswara College of Pharmacy, Ootacamund, Tamil Nadu, Jagadguru Sri Shivarathreeswara University, Mysore, Karnataka, India
2 Dermatologist, Govt. District Head Quarters Hospital, Ootacamund, Tamil Nadu, India

Correspondence Address:
Ponnusankar Sivasankaran
Professor and Head, Department of Pharmacy Practice, Jagadguru Sri Shivarathreeswara College of Pharmacy, Udhagamandalam 643 001, Tamil Nadu, Jagadguru Sri Shivarathreeswara University, Mysore - 570 015, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-344X.154911

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Porphyria cutanea tarda (PCT) is the most frequent type of porphyria worldwide and presents with skin symptoms only. Porphyrias are a group of eight panethnic inherited metabolic disorders of heme biosynthesis. Porphyria can affect peripheral, autonomic, and central nervous systems.In porphyria conditions there is accumulation of the hemeprecursor's 5-aminolaevulinic acid, porphobilinogen, and porphyrins; which are associated with characteristic clinical feature with acute neurovisceral attacks and skin lesions. Variegate porphyria, hereditary coproporphyria, and PCT share the same chronic cutaneous photosensitivity. Some drugs will also induce acute attack of porphyria. This report summarizes the management of PCT with a focus on the signs and symptoms and finding that might help and prevent unnecessary medications.

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