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Year : 2018  |  Volume : 7  |  Issue : 3  |  Page : 184-190

A study comparing cognitive function assessment in type-2 diabetes mellitus using Rowland Universal Dementia Assessment Scale and Mini Mental State Examination

1 Department of Pharmacology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India
2 Department of Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India

Correspondence Address:
Dr. S Shanmugapriya
Department of Pharmacology, PSG Institute of Medical Sciences and Research, Off Avinashi Road, Peelamedu, Coimbatore - 641 004, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijhas.IJHAS_10_18

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BACKGROUND: Diabetes mellitus is a metabolic disorder which can predispose to cognitive impairment. It is important to screen diabetic patients for cognitive dysfunction in the routine clinical management. Our study aimed at comparative evaluation of commonly used cognition assessment tools such as Mini Mental State Examination (MMSE) and Rowland Universal Dementia Assessment Scale (RUDAS) in diabetes patients. METHODS: The study was conducted as a prospective case–control design in a tertiary care teaching hospital from March to October 2015. After obtaining written informed consent, the data on demographic details, duration of diabetes, and glycemic control marked by glycated hemoglobin were recorded. A total of 101 previously diagnosed type-2 diabetes patients and an equal number of age-, gender-, and literacy-matched controls without diabetes were administered the MMSE and RUDAS cognition scales in a one-to-one interview by a trained diabetic educator who was blinded to the groups. RESULTS: The study revealed that there was a significant difference in cognition scores between the diabetic patients with short duration (<5 years) and those with a longer history of diabetes (≥5 years) only in the MMSE scale using independent sample t-test (P = 0.018), unlike the RUDAS in which the difference was insignificant (P = 0.235). Similarly, there was also a significant correlation between glycemic control and cognition scores in the MMSE (P = 0.03), but not in the RUDAS scale (P = 0.083). CONCLUSION: MMSE scale has been proved to be advantageous over the RUDAS as a screening tool for cognition assessment in diabetes patients.

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