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Year : 2018  |  Volume : 7  |  Issue : 4  |  Page : 266-269

Dysplastic cerebellar gangliocytoma (Lhermitte–Duclos disease) in the immediate postpartum period

Department of Neurosurgery, The Grant Government Medical College, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Prashant S Gade
Department of Neurosurgery, The Grant Government Medical College, Mumbai, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijhas.IJHAS_16_18

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Lhermitte–Duclos disease, also known as dysplastic cerebellar gangliocytoma, is a rare lesion of the cerebellar cortex with both neoplastic and hamartomatous features. A “tiger-striped” cerebellar lesion with unilateral hemispheric expansion and preservation of the gyral pattern is a characteristic finding on magnetic resonance imaging brain. It usually occurs in the setting of Cowden's syndrome, an autosomal dominant condition characterized by multiple hamartomas and neoplastic lesions in skin and internal organs. Evolution of dysplastic cerebellar gangliocytoma during pregnancy is not well known, given its rarity. We describe a young female who presented in the immediate postpartum period with acute hydrocephalus secondary to the left cerebellar gangliocytoma and was treated successfully with surgery. The background setting of Cowden's syndrome was not present in our case.

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