%A Jawarkar, Ajay
%A Lokare, Pushpa
%A Kizhatil, Anuradha
%A Jawarkar, Jyoti
%A Kale, Sandhya
%T Study on effectiveness and outcome of mifepristone and misoprostol in medical termination of pregnancy
%9 Original Article
%D 2017
%J International Journal of Health & Allied Sciences
%R 10.4103/2278-344X.200200
%P 35-38
%V 6
%N 1
%U https://www.ijhas.in/article.asp?issn=2278-344X;year=2017;volume=6;issue=1;spage=35;epage=38;aulast=Jawarkar
%8 January 1, 2017
%X BACKGROUND: One of the most effective and safest medical abortion (MA) regimens consist of the use of a combination of mifepristone and misoprostol. Misoprostol can be administrated by oral or vaginal route after giving a single dose of mifepristone. The present study was conducted to assess the effectiveness and complications by these two routes.
SUBJECTS AND METHODS: The present study was nonrandomized clinical trial conducted at two private hospitals and medical college, Amravati city. The women having a history of amenorrhea ≤49 days and who were willing for medical termination of pregnancy by MA pills method were included in the study during the 1-year after obtaining ethical approval. The women in both groups were given tablet mifepristone (200 mg day) on day 1 orally followed by tablet misoprostol (two tablets of 200 μg) on day 3 orally in one group and vaginally in other group.
RESULTS: The success rate of medical termination in group with oral administration of misoprostol was 96.3% as compared to 97.7% success rate in group with vaginal administration of misoprostol. The gastrointestinal side effects were 41.4% in group with oral administration of misoprostol as compared to 21.7% in group with vaginal administration of misoprostol. The Chi-square test of significance was applied using SPSS software version 16.0.
CONCLUSIONS: The success of medical termination of pregnancy was comparable in both groups with slightly higher success rate by vaginal route of administration of misoprostol.
%0 Journal Article
%I Wolters Kluwer Medknow Publications
%@ 2278-344X