Correspondence Address:
Dr. Anubhav Chauhan
Pine Castle, Near Mist Chamber, Khalini, Shimla - 171 002, Himachal Pradesh
India

Full Text

Sir,

We read with great interest the excellent article by Agrawal et al. entitled, "Rare occurrence of bortezomib-induced Sweet's syndrome in multiple myeloma."[1] We applaud the authors for diagnosing and managing the rare entity but would like to add interesting information which has not been presented.

It may also be associated with a viral upper respiratory tract infection, autoimmune diseases, inflammatory bowel diseases, and pregnancy.[2] Incidence is usually in the fourth or fifth decade with a peak in January and February. Sweet's syndrome accounts for 4/1000 new cases in a dermatological unit. It is five times more common in females than males.[3]

Involvement of the eyes, joints, oral mucosa, lungs, liver, kidneys, and central nervous system has been described.[4] Ocular involvement most commonly is in the form of conjunctivitis, others being periorbital and orbital inflammation, dacryoadenitis, episcleritis, scleritis, limbal nodules, peripheral ulcerative keratitis, iritis, glaucoma, and choroiditis. The ocular inflammation appears concurrently with skin lesions.[5]

Second, the diagnostic criteria for Sweet's syndrome have not been clearly stated by the respected authors. Diagnostic criteria for classical Sweet's syndrome versus drug-induced Sweet's syndrome are shown in [Table 1]. [6]{Table 1}

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