International Journal of Health & Allied Sciences

CASE REPORT
Year
: 2017  |  Volume : 6  |  Issue : 4  |  Page : 228--229

Imerslund-Grasbeck syndrome presenting as pancytopenia: A rare case report


Pravesh Agarwal, Subhash Chand, Deveshwar Pandey 
 Department of Medicine, Dr. Yashwant Singh Parmar Government Medical College, Nahan, Himachal Pradesh, India

Correspondence Address:
Dr. Pravesh Agarwal
H.N. 1652/6, Near S.E.P.W.D, Circle Office, Nahan, District-Sirmour, Himachal Pradesh - 173 001
India

Imerslund-Grasbeck syndrome or selective Vitamin B12 malabsorption with proteinuria or megaloblastic anemia 1 is a rare autosomal recessive disorder. The main feature of this condition is megaloblastic anemia due to Vitamin B12 deficiency with or without persistent proteinuria (with no signs of kidney disease). The disease appears from 4 months up to several years after birth. The cause is a defect in the receptor of the Vitamin B12-intrinsic factor complex of the ileal enterocytes. Management includes lifelong parenteral Vitamin B12, and with this, the patients remain healthy for decades. However, the proteinuria persists. We present a 14-year-old male child suffering from this syndrome presenting to us with pancytopenia due to Vitamin B12 deficiency and proteinuria with normal kidneys. There is hardly any case report of this syndrome from North India.


How to cite this article:
Agarwal P, Chand S, Pandey D. Imerslund-Grasbeck syndrome presenting as pancytopenia: A rare case report.Int J Health Allied Sci 2017;6:228-229


How to cite this URL:
Agarwal P, Chand S, Pandey D. Imerslund-Grasbeck syndrome presenting as pancytopenia: A rare case report. Int J Health Allied Sci [serial online] 2017 [cited 2024 Mar 29 ];6:228-229
Available from: https://www.ijhas.in/article.asp?issn=2278-344X;year=2017;volume=6;issue=4;spage=228;epage=229;aulast=Agarwal;type=0